One possible reason: CRISPR is a much larger molecule, and the comparatively smaller meganucleases are easier to package and deliver to nerve cells. It takes about three months to make a meganuclease," Stoddard said. Experience has shown, however, that the Jerome Lab is endowed with patience. Their year trek has proven the potential of gene therapy for erasing herpes, yet the road ahead will undoubtedly require deep reserves of patience and persistence.
Meganucleases used in the experiments described in the Nature Communications paper were supplied by Paris-based Cellectis SA. Note: Scientists at Fred Hutch played a role in developing these discoveries, and Fred Hutch and certain of its scientists may benefit financially from this work in the future.
Reach him at srussell fredhutch. Are you interested in reprinting or republishing this story? Be our guest! We want to help connect people with the information they need.
Email us at communications fredhutch. Donate Now. Hutch News Stories. A cure for herpes? There is progress to report. Mouse studies show gene therapy can cause big drop in latent infections.
Martine Aubert, a senior staff scientist in the Fred Hutch laboratory of Dr. Keith Jerome, carried out the meticulous research that steadily improved the results of efforts to eradicate herpes simplex virus in mice. It takes a persistent scientist to stop a persistent virus. Nevertheless, she persisted. What breakthroughs are coming next? Sign up for news. Facebook Twitter LinkedIn Syndicate. Genital Herpes Treatment and Care. Minus Related Pages. Medicine can reduce symptoms and the chance of spreading it to others.
Is there a cure or treatment for genital herpes? October 5, Related Content. STDs Home Page. An antiviral cream or ointment can relieve the burning, itching, or tingling. An antiviral medicine that is oral pills or intravenous shot can shorten an outbreak of herpes. Prescription antiviral medicines approved for the treatment of both types of herpes simplex include:.
Taken daily, these medicines can lessen the severity and frequency of outbreaks. They also can help prevent infected people from spreading the virus. The first primary outbreak of herpes simplex is often the worst. Not all first outbreaks are severe, though. Some are so mild that a person does not notice. When the first outbreak of genital herpes is mild and another outbreak happens years later, the person can mistake it for a first outbreak.
Some people have one outbreak. For others, the virus becomes active again.
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